Methylene blue dye Manufacturers

Methylene blue dye

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Product Details:

Product Description

Methylthioninium chloride, commonly called methylene blue, is a salt used as a dye and as a medication.Methylene blue is a thiazine dye. As a medication, it is mainly used to treat methemoglobinemia by converting the ferric iron in hemoglobin to ferrous iron.Specifically, it is used to treat methemoglobin levels that are greater than 30% or in which there are symptoms despite oxygen therapy.It has previously been used for cyanide poisoning and urinary tract infections, but this use is no longer recommended.

Medical uses-

Methemoglobinemia

Methylene blue dye is employed as a medication for the treatment of methemoglobinemia, which can arise from ingestion of certain pharmaceuticals, toxins, or broad beans.[7] Normally, through the NADH or NADPH dependent methemoglobin reductase enzymes, methemoglobin is reduced back to hemoglobin. When large amounts of methemoglobin occur secondary to toxins, methemoglobin reductases are overwhelmed. Methylene blue, when injected intravenously as an antidote, is itself first reduced to leucomethylene blue, which then reduces the heme group from methemoglobin to hemoglobin. Methylene blue can reduce the half life of methemoglobin from hours to minutes. At high doses, however, methylene blue actually induces methemoglobinemia, reversing this pathway.

Methylphen

Hyoscyamine/­hexamethylenetetramine/­phenyl salicylate/­methylene blue/­benzoic acid (trade names Methylphen, Prosed DS) is a drug combination. It is not safe or effective for any medical purpose

Cyanide poisoning

Since its reduction potential is similar to that of oxygen and can be reduced by components of the electron transport chain, large doses of methylene blue are sometimes used as an antidote to potassium cyanide poisoning, a method first successfully tested in 1933 by Dr. Matilda Moldenhauer Brooks in San Francisco,[10] although first demonstrated by Bo Sahlin of Lund University, in 1926.